Bethan Manley, lead Computational biologist at Spun, said the aim was to "improve confidence in woodland creation" by "working with natural processes".
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At this point, each bound sequence exists as a single copy, which produces too faint a signal to detect reliably. Colony sequencing solves this by generating clusters of identical fragments through a process called bridge amplification. The adapter on the free end of each DNA strand will be complementary to some of the original, short sequences on the DNA lawn, and when this binding occurs, the strand bends over to form a bridge shape. Another round of amplification takes place, resulting in two complementary strands each directly affixed to the flow cell. This “bridge amplification” process is repeated over and over to propagate the sequence.，详情可参考爱思助手下载最新版本
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